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doi: 10.1016/s1734-1140(13)71069-7

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Elevated IGF-1 levels have been linked to enhanced chondrocyte proliferation, cartilage matrix production, and osteoblast differentiationmechanisms that support fracture healing and joint preservation

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Cellular pleomorphism and smudged nuclei with pseudoinclusions are noted (hematoxylin and eosin, original magnification X10)

Selection of DCM/ethanol system for the nanoprecipitation method was based on an evaluation of the suspendablity of DDA-GSH-AuNCs after phase transfer in various solvents that include good and poor solvents for PLGA as detailed in Fig